Synaptophysin is involved in resetting of the mammalian circadian clock
نویسندگان
چکیده
منابع مشابه
Synaptophysin is involved in resetting of the mammalian circadian clock
BACKGROUND Mammals can adapt to changing light/dark conditions by advancing or delaying their circadian clock phase. Light pulses evoke changes in gene expression and neuronal activity in the suprachiasmatic nuclei (SCN), the central pacemaker of the circadian system. Alterations in neuronal activity are partially mediated by changes in synaptic vesicle (SV) fusion at the presynaptic membrane, ...
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The suprachiasmatic nuclei (SCN) contain the principal circadian clock governing overt daily rhythms of physiology and behavior. The endogenous circadian cycle is entrained to the light/dark via direct glutamatergic retinal afferents to the SCN. To understand the molecular basis of entrainment, it is first necessary to define how rapidly the clock is reset by a light pulse. We used a two-pulse ...
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ژورنال
عنوان ژورنال: Journal of Circadian Rhythms
سال: 2013
ISSN: 1740-3391
DOI: 10.1186/1740-3391-11-11